Abstract:
A comparative study was carried out to decide the hypoxia tolerance limit, microstructure and ultrastructure variations on cardiac muscle tissue under hypoxia process for Gansu zokor and SD rats. The results showed that: at 30%,35%,40% and 45% of the oxygen concentration, the average survival time for SD rats was 028±007,048±008,487±04 and 560±076 h, respectively;that for Gansu zokor was 103±014,204±027,10 and 10 h respectively; at the oxygen concentration of 40% ,the injury of LV(left ventricle) microstructure and ultrastructure for Gansu zokor was gradually worsened after 2 and 4 h of hypoxia, then began to recover after 6 h and restored to the control group status at 10 h.However, for SD rats, both the cardiac muscle microstructure and ultrastructure of LV were irrevocably changed after 4 h of hypoxia(40%) . Thus it can be inferred that the oxygen concentration of 40% was close to hypoxia tolerance limit in normal life for Gansu zokor. Under the oxygen concentration of 40% ,the Gansu zokor had potential to mobilize mechanism of compensatory to cope with the acute hypoxia enviroment.
