Expression change of Bax、Bcl-2 in the hippocampus neuron of rats after long-term stop trained
ZHAO Yong-shou1, TIAN Zhen-jun2*, BAI Jian-chao1
(1 Department of Physical Education, Shaanxi Institute of Education, Xi′an 710061,Shaanxi, China;2 College of Physical Education, Shaanxi Normal University, Xi′an 710062, Shaanxi, China)
Abstract:
The influence on the expression of Bax、Bcl-2 in the hippocampus neuron of stopping training 28 weeks rats is studied. Refered to the training scheme of Bedford, the training model of SD rats is established. All rats in the normal cage live 28 weeks and the expression change of Bax and Bcl-2 in the Hippocampus Neuron is observed. The results show that aerobic training promotes the ratio of Bcl-2/Bax in CA1 area and CA3 area of hippocampus, fatigue training restrain the ratio of Bcl-2/Bax in CA1 area and CA3 area of hippocampus after stopping training. It is analyzed that aerobic training has taken good care of the hippocampus neuron of the aged rats, fatigue training has effected the function of the hippocampus neuron of the aged rats.
KeyWords:
sports training; hippocampus; Bax; Bcl-2; stopping training; Immunohisyochemistry