JIA Gui-dong , YANG Jian-xiong*,WANG Li ,FAN Jin
(College of Life Science, Shaanxi Normal University, Xi′an 710062, Shaanxi, China)
Abstract:
In order to investigate synergistic antioxidative activities of rutin and chlorogenic acid(CGA), the antioxidative activities of the mixture of rutin and CGA with different ratio were measured, including the scavenging activities against 1,1-diphenyl-2-picrylhydrazyl (DPPH) and superoxide anion (O-·2) free radicals, and also inhibitory ability against lipid peroxidation induced by Fe2+. The results showed that combinations between rutin and CGA had better antioxidative activity. The highest synergistic effects (the tatio of experimental scavenging to theoretical scavenging) in three different assay systems were 121 (DPPH), 138 (O-·2), and 112 (lipid peroxidation), respectively.
KeyWords:
chlorogenic acid(CGA); rutin; synergistic effect; antioxidant; 1,1-diphenyl-2-picrylhydrazyl