Studies on antioxidant activities of ethanoic extract from defatted Semen astragali complanati in vitro
WANG Li1, LIU Jing2, YANG Jian-xiong1*
(1 College of Life Science, Shaanxi Normal University, Xi′an 710062, Shaanxi, China;2 Department of Biology, Shaanxi Education College, Xi′an 710061, Shaanxi, China)
Abstract:
In-vitro antioxiant activities of ethanoic extract from defatted Semen astragali complanati (ESA) have been investigated employing antioxidant activities in different systems including free radical scavenging activities on α,α-diphenyl-β-picrylhydrazyl (DPPH·),super anion radical(O-·2), and hydroxyl radical(·OH), inhibition activity of Fe2+ induced lipid peroxidation, reducing power, and total antioxidant capacity, and the antioxidant activities have been compared with standard antioxidant L-ascorbic acid. The results show that ESA has a certain scavenging activity of DPPH· (IC50=4191 μg/mL), a strong to super anion radical (IC50=1179 μg/mL) and hydroxyl radical(IC50=2244 μg/mL), a good inhibition activity against the lipid peroxidation(IC50=170 mg/mL), and an excellent total antioxidant capacity. As a result, ESA has strong antioxidant activities.
KeyWords:
Semen astragali complanati; antioxidant activity; free radical; lipid peroxidation