碱性介质中双嘧达莫荧光特性研究-陕西师范大学学报期刊社网站

陕西师范大学学报（自然科学版）

化学与材料科学

碱性介质中双嘧达莫荧光特性研究

程冬梅,巨芸,李保新*

(陕西师范大学化学与材料科学学院, 陕西西安 710062)

程冬梅，女，硕士研究生，主要从事荧光分析研究．

摘要:

研究了双嘧达莫在酸性、中性和碱性介质中的荧光性质，发现在碱性介质中双嘧达莫有最大的荧光强度．据此，建立了一种简单灵敏的双嘧达莫荧光分析新方法．结果表明，双嘧达莫的线性范围为1.0×10-9～1.0×10-7 g/mL，检出限为3.0×10-10 g/mL．此外，通过测定双嘧达莫在不同介质中的荧光量子产率，解释了在碱性介质中双嘧达莫具有强荧光特性的原因．

关键词：

双嘧达莫；荧光光谱；荧光量子产率

收稿日期：

2008-05-16

中图分类号：

O657.3

文献标识码：

文章编号：

1672-4291(2009)03-0054-03

基金项目：

国家自然科学基金资助项目（20405009）；教育部新世纪优秀人才资助计划项目

Doi:

Investigation on fluorescence property of dipyridamole in basic medium

CHENG Dong-mei, JU Yun, LI Bao-xin*

(College of Chemistry and Materials Science, Shaanxi Normal University, Xi′an 710062, Shaanxi,China)

Abstract:

The fluorescence properties of dipyridamole were studied in acidic, neutral and basic medium. It was found that the fluorescence intensity of dipyridamole in basic medium is the strongest among the media we studied. Based on the phenomena, a simple and sensitive fluorometric method for determination of dipyridamole was developed. The linear range of this method was 1.0×10-9～1.0×10-7 g/mL, and the detection limit was 3.0×10-10 g/mL. Furthermore, the fluorescence quantum yields of dipyridamole in various media were measured in order to explain the phenomena.

KeyWords:

dipyridamole; fluorescence spectrum; fluorescence quantum yield