DAI Bin1, YANG Jian-xiong1*, ZHANG Zun-ting2, ZHU Yao-hua3
(1 College of Life Science, Shaanxi Normal University; 2 College of Chemistry and Material Science, Shaanxi Normal University; 3 College of Physics and Information Technology, Shaanxi Normal University, Xi′an 710062, Shaanxi, China)
Abstract:
The antioxidant activity of HAMP［3-(2-hydroxy-4-methoxyphenyl)-4-(3-amine and-4-methoxyphenyl) pyrazole］ was investigated by employing several assay systems in vitro, including scavenging 1,1-diphenyl-2-picrylhydrazyl radical (DPPH·), superoxide anion radical, reduction, restraining peroxidations of polyunsaturated fatty acid from yolk lipoprotein induced by Fe2+ and β-carotene/linoleic acid. The results showed that HAMP had a strong ability to scavenge O-·2 and to restrain of lipid peroxidation. As a result, HAMP can be used as antioxidant.
KeyWords:
HAMP; in vitro antioxidant activity; superoxide anion radical; lipid peroxidation; reduction
