沙苑子对运动训练大鼠骨骼肌自由基代谢的影响-陕西师范大学学报期刊社网站

陕西师范大学学报（自然科学版）

专题研究

沙苑子对运动训练大鼠骨骼肌自由基代谢的影响

王轲1，熊正英2,*，王家彬1

(1 西北工业大学体育部，陕西西安 710072；2 陕西师范大学运动生物学研究所，陕西西安 710062)

王轲，男，讲师，硕士，主要从事运动生物化学与营养学方面的研究．*通讯作者：熊正英，男，教授．

摘要:

通过建立力竭跑台训练模型，测试大鼠骨骼肌组织超氧化物歧化酶(SOD)、过氧化氢酶（CAT）活性、谷胱甘肽过氧化物酶(GSH-Px)活性、丙二醛(MDA)含量和ATP酶活性，探讨沙苑子对力竭跑台训练大鼠骨骼肌组织自由基代谢、ATP酶活性和运动能力的影响．结果显示，与安静组比较，运动力竭组SOD、CAT和GSH-Px活性降低，MDA含量升高；沙苑子组大鼠骨骼肌组织活性显著高于对照组, MDA含量明显低于相应对照组(P<001)；运动力竭组Na+、K+-ATPase和 Ca2+、Mg2+-ATPase活性与安静组比较降低，沙苑子组大鼠骨骼肌组织ATPase活性显著高于对照组．沙苑子可显著提高运动大鼠抗氧化的功能，提高运动大鼠骨骼肌组织ATPase活性,具有较强抗氧化能力,使大鼠运动能力有了明显提高．

关键词：

沙苑子；力竭运动训练；自由基； ATP酶；骨骼肌；大鼠

收稿日期：

2006-03-12

中图分类号：

G804.7

文献标识码：

文章编号：

1672-4291(2007)01-0103-04

基金项目：

陕西省自然科学基金资助项目（2003C137）；西北工业大学青年教师创新基金资助项目（MO16202）

Doi:

Effect of astragalus complanatus on metabolism of free radicals in the skeletal muscles of training rats

WANG Ke1, XIONG Zheng-ying2, WANG Jia-bin1

(1 Physical Education and health Section, Northwest Polytechnical University, Xi′an 710072, Shaanxi, China;2 Institute of Sports Biology, Shaanxi Normal University, Xi′an 710062, Shaanxi, China)

Abstract:

The research was to measure SOD and CAT activity, GSH-Px activity, MDA amount and ATPase activity in the skeletal muscle tissues of the rats in the exhaustive exercise training. The effects of astragalus complanatus on metabolism of free radicals, ATPase activity in the skeletal muscles of the exhaustive exercise training rats and the exercising performance of the rats were discussed. The results show: (1) Compared with quiet group, SOD, CAT and GSH-Px activities of the exhaustive exercise training group decrease, whereas MDA amount increases. The skeletal muscles of the rats in astragalus complanatus group are much more active than those of the rats in compared group. MDA amount is obviously lower than that of compared group (P

KeyWords:

astragalus complanatus; exhaustive exercise training; free radicals; ATPase; skeletal muscle; rats