Abstract:
To research the effect of cadmium on the renal microstructure of amphibian, Rana chensinensis were subcutaneously injected in different doses of Cd2+ solution every 48 hours, the change in renal microstructure was observed employing an optical microscope. The results showed that for the dose of 0.1 mg/kg Cd2+ solution, no distinct change was observed in epithelia of the renal tubules, for the doses of 0.25 mg/kg, 0.5 mg/kg, 1 mg/kg and 2.5 mg/kg Cd2+ solution, the epithelia of proximal renal tubules displayed swelling, distortion and vacuolar casts in different degree, for the doses of 6 mg/kg and 12 mg/kg Cd2+ solution, the proximal renal tubule necrotized, cells of the distal convoluted tubule and the glomeruli distorted to some extent. The results indicate that the kidney of amphibian is damaged more severely with increase in the doses of cadmium and time treated.
