核桃油对小鼠学习记忆能力的影响-陕西师范大学学报期刊社网站

陕西师范大学学报（自然科学版）

专题研究

核桃油对小鼠学习记忆能力的影响

张清安，李建科，范学辉

(陕西师范大学食品工程系，陕西西安 710062)

张清安,男,讲师, 主要从事食品分析检验方面的研究．

摘要:

以不同剂量核桃油给小鼠灌胃，每天1次连续2周，在被动回避装置上测定小鼠的跳台潜伏期（SDL）和逃避潜伏期（EL），在复杂迷宫上测定小鼠的觅食时间．结果显示，核桃油可使SDL延长30.4%～102.5%，使EL缩短35.3%～58.9%,使迷宫觅食时间减少3.3%～37%,并能明显改善NaNO2和乙醇引起的记忆损害；表明核桃油可明显改善小鼠学习记忆能力．

关键词：

核桃油；小鼠；学习记忆

收稿日期：

2006-01-12

中图分类号：

R151.1

文献标识码：

文章编号：

1672-4291(2006)04-0089-03

基金项目：

陕西师范大学校级重点科研基金资助项目

Doi:

Effects of walnut oil on learning and memory of mice

ZHANG Qing-an, LI Jian-ke, FAN Xue-hui

(Department of Food Engineering, Shaanxi Normal University, Xi′an 710062, Shaanxi, China)

Abstract:

Mice were given different doses of walnut oil once a day lasting two weeks. Their step-down latency (SDL) and escaping latency (EL) in a passive avoidance device, and food-hunting time in a maze were determined. The results showed that walnut oil lengthened SDL by 30.4%～102.5%, shortened EL by 35.3%～58.9% and food-hunting time by 3.3%～37%. At the same time, Walnut oil reversed the disruption of memory induced by NaNO2 and ethanol, which meant that walnut oil could obviously improve the learning and memorizing ability of mice.

KeyWords:

walnut oil; mouse; learning and memory