Synthesis and antibacterial activities of two novel holmium(Ⅲ) and dysprosium(Ⅲ) complexes with benzoyl hydrazone ligand
GAO Xia1,2*, QIAO Chengfang1*, LIU Yongliang1, ZHOU Chunsheng1,ZHANG Guochun1
(1 Shaanxi Key Laboratory of Comprehensive Utilization of Tailings Resources, Department of Chemical Engineering and Modern Materials, Shangluo University, Shangluo 726000, Shaanxi, China;2 Laboratory of Macromolecular Science of Shaanxi Province, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi′an 710119, Shaanxi, China)
Abstract:
A novel hydrazone ligand pyruvate-3-methoxy benzoyl hydrazone (PMBH) has been synthesized from pyruvic acid and 3-methoxybenzhydrazide in anhydrous alcohol. The conventional solution reaction of PMBH with rare earth ions (RE3+=Ho3+ and Dy3+) in water-ethanol solvent was carried out to generate two novel complexes:\[Ho(PMBH)3\]\[Ho′(PMBH)3\] (1)and\[Dy(PMBH)3\]\[Dy′(PMBH)3\]·2CH3OH·H2O(2).The structures and properties of the two complexes were investigated by means of elemental analysis, X-ray powder diffraction (XRPD), X-ray single-crystal diffraction, fourier-transform infrared spectroscopy (FT-IR) and thermogravimetric analysis(TGA). The antibacterial activities of PMBH ligand and its complex 1 and 2 against Fusarium solani were investigated by colony diameter method. The results showed that they all demonstrated antibacterial activities against Fusarium solani, and complex 1 and 2 have much stronger antibacterial activities than that of the PMBH ligand.
KeyWords:
holmium(Ⅲ); dysprosium(Ⅲ); complex; pyruvate-3-methoxy benzoyl hydrazone; antibacterial activity