自然科学版
陕西师范大学学报(自然科学版)
新型冠状病毒肺炎研究专题
基于改进SIR模型的新型冠状病毒肺炎疫情预测及防控对疫情发展的影响
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朱仁杰, 唐仕浩, 刘彤彤, 郭燕, 董珊珊, 成瀛*, 杨铁林*
(西安交通大学 生命科学与技术学院 生物医学信息工程教育部重点实验室, 陕西 西安 710049)
杨铁林,男,教授,博士生导师,从事生物信息与遗传学研究。E-mail: yangtielin@xjtu.edu.cn;成瀛,男,副教授,博士生导师,从事分子生物学与疾病机制研究。E-mail:yingcheng@xjtu.edu.cn
摘要:
基于约翰·霍普金斯大学系统科学与工程中心获取的2020年3月4日至4月4日期间意大利、韩国、英国、美国、法国、西班牙、德国等7个疫情比较严重国家的新型冠状病毒肺炎(COVID-19)确诊、死亡、治愈病例数据,以SIR模型为基础,通过添加新的参数表征感染系数随时间的变化,并利用回归分析进行参数估计,对7个国家疫情的发展情况进行模拟和预测,并分析各国控制接触率等防治措施对于疫情发展的影响。结果表明:改进的SIR模型对COVID-19疫情发展趋势的分析基本可靠;除英国和美国以外,其他5个国家的疫情现阶段已经得到初步控制,而英国和美国还需要加强防控,以减少疫情带来的损失。研究结果证实了在COVID-19疫情防控中,采取减少集会、避免接触、集中收治等降低人群接触率措施的重要性,以期为后续疫情防控提供参考。
关键词:
SARS-CoV-2;COVID-19;SIR模型;疫情分析;接触率;防控措施
收稿日期:
2020-04-07
中图分类号:
R181.8;O212
文献标识码:
A
文章编号:
1672-4291(2020)03-0033-06
基金项目:
中央高校基础科研业务费新型冠状肺炎应急科研项目(xzy032020039,xzy032020023)
Doi:
COVID-19 epidemic prediction based on improved SIR model and the impact of prevention and control on epidemic development
ZHU Renjie, TANG Shihao, LIU Tongtong, GUO Yan, DONG Shanshan, CHENG Ying*, YANG Tielin*
(Key Laboratory of Biomedical Information Engineering of Ministry of Education, College of Life Science and Technology, Xi′an Jiaotong University, Xi′an 710049, Shaanxi, China)
Abstract:
The data of confirmed cases, death cases and cured cases of coronavirus disease 2019 (COVID-19) in seven epidemic seriously affected countries (Italy, South Korea, the United Kingdom, the United States, France, Spain, Germany) were obtained from the System Science and Engineering Center at Johns Hopkins University. Data were collected between March 4, 2020 and April 4, 2020. Traditional SIR model was used and improved by adding a new parameter to characterize the infection coefficient changes over time, and regression analysis was introduced to estimate the parameters. Based on the improved SIR model, the development of COVID-19 in 7 countries were simulated and predicted, and the effects of contact rate control measures of different countries on epidemic development were analyzed. Results showed that the improved SIR model was reliable for analyzing the epidemic trend of COVID-19. Apart from the United Kingdom and the United States, the other five countries have had their pandemic under initial control, while the United Kingdom and the United States need to do more to reduce the pandemic damage. Our finding confirmed the importance of reducing population contact rate in COVID-19 prevention and control, such as reducing assembly, avoiding contact and centralized admission, so as to provide reference for the subsequent epidemic prevention and control.
KeyWords:
SARS-CoV-2; COVID-19; SIR model; epidemic analysis; contact rate; prevention and control measures