Abstract:
The rare earth Europium-doped spherical mesoporous bioactive glass(Eu3+-SMBGs) was successfully prepared by hydrothermal method under the catalysis of nitric acid, and the loading and release ability of the drug molecules Ibuprofen(IBU) of Eu3+-SMBGs was studied. XRD, FTIR, SEM, N2 adsorption/desorption, and PL spectra were employed to characterize the as-prepared materials. The results reveal that the spherical products have porous structure with an average diameter of 80 μm and possess strong red luminescence of Eu3+ under UV irradiation. Drug release test reveals that the spherical bioactive glass system has favorable drug loading and sustained release properties with Ibuprofen as the model drug. In addition, IBU-loaded samples show red luminescence under UV irradiation, and the photoluminescence intensities vary with the released amount of IBU.
