LI Yuntao1, GUO Ning1, SHEN Wen2
（1 College of Chemistry and Chemical Engineering; 2 College of Life Science and Engineering, Shaanxi University of Science and Technology, Xi′an 710021, Shaanxi, China）
Abstract:
Avermectin entrapped in HP-β-cyclodextrin was investigated.The water was selected as medium to prepare the inclusion compound.Employing single factor and orthogonal tests, the best conditions of inclusion process were determined as follows: the feeding quality ratio being 100∶3, inclusion temperature at 50 ℃, inclusion time for 8 h. Under these conditions, it was determined by HPLC that the inclusion efficiency was 39.6%, and the yield was 81.1%. The inclusion compound was analysed by TG. The results show that the light stability and solubility in water of avermectin entrapped in HP-β-cyclodextrin increase significantly compared with avermectin.The long-term performance of avermectin's insecticidal and acaricidal properties are improved significantly.
KeyWords:
avermectin; HP-β-cyclodextrin; inclusion
