Abstract:
This review focused on the production of microRNA (miRNA) and its relationship with tumorigenesis and their potential as diagnostic, prognostic, and therapeutic tools. It has been revealed that miRNA can regulate the function of oncogene and/or anti-oncogene, which has a close relationship with the development of tumor. At the same time, miRNA plays an important role in tumor diagnosis, tumor prognosis and tumor therapy. The future direction of the field will focus the target identification of new miRNA, the study of molecular mechanisms involved in the development of diseases and the screening and validation of specific miRNAs for the diagnosis, prognosis and therapy of certain diseases.
