自然科学版
陕西师范大学学报(自然科学版)
运动与健康促进专题
不同运动干预下老年肌少症患者的CT影像特征变化
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魏渼淇1,杨光1*,魏茂泉2,孟德宇1,何诗纯1,李妍2
(1 东北师范大学 体育学院,吉林 长春 130000;2 白山市中心医院 放射科,吉林 白山 134300)
杨光,男,教授,博士生导师,研究方向为运动与健康促进。E-mail: yangg100@nenu.edu.cn
摘要:
为研究不同运动干预下老年肌少症患者的CT影像特征变化,招募60~75岁的肌少症患者92例,随机分为有氧训练(AT)组、抗阻训练(RT)组和空白对照(CG)组;AT组与RT组实施运动处方干预,CG组接受常规护理管理,干预周期20周;干预前、后1周内对患者各进行1次上腹部CT扫描,定量测量L3椎体水平骨骼肌面积(L3 SMA)、密度(L3 SMD)和肌间隙脂肪面积、密度并计算骨骼肌脂肪浸润程度(MFI),比较3组研究对象干预前后的影像学指标差异。结果表明:运动可有效延缓肌少症发展,RT的干预效果优于AT;RT可有效改善甚至逆转老年人与年龄有关的骨骼肌肌量进行性下降;AT与RT均有助于预防老年人与年龄相关的肌间脂肪积累,但无法实现肌间脂肪积累的逆转。
关键词:
老年人;肌少症;运动;CT
收稿日期:
2022-06-22
中图分类号:
R685;G804.2
文献标识码:
A
文章编号:
1672-4291(2022)06-0095-09
基金项目:
国家社会科学基金(16BTY076)
Doi:
10.15983/j.cnki.jsnu.2022219
Changes in CT features of elderly patients with sarcopenia under different exercise interventions
WEI Meiqi1, YANG Guang1*, WEI Maoquan2,MENG Deyu1, HE Shichun1,LI Yan2
(1 School of Physical Education, Northeast Normal University, Changchun 130000, Jilin, China;2 Department of Radiology,Baishan Central Hospital,Baishan 134300,Jilin, China)
Abstract:
The effects of different exercise interventions on patients with sarcopenia based on multislice spiral CT imaging are investigated.92 patients aged 60~75 years with sarcopenia were recruited and randomly divided into an aerobic training(AT) group, a resistance training(RT) group and a blank control(CG) group.Both of AT and RT groups implemented the exercise prescription intervention while CG group received usual care management. The intervention period was 20 weeks.One CT scan of the upper abdomen was performed on the patient one week before and one week after the intervention to measure L3 SMA、L3 SMD as well as area and density of inter-muscular fat, and then to compare the differences in imaging indices between the three study groups before and after the intervention.The results show that exercise can effectively delay the development of sarcopenia, RT have a better effect than AT. RT can effectively improve or even reverse age-related progressive decline in skeletal muscle mass. Both AT and RT help to prevent age-related inter-muscular fat accumulation in older people, but cannot be reversed.
KeyWords:
older people; sarcopenia; exercise; CT